How to use Clomid for Infertility caused due to ovulatory Dysfunction?

Clomid or Clomiphene citrate is a world famous generic medicine, used for the treatment of infertility caused due to ovulatory dysfunction in women seeking pregnancy. Clomiphene Citrate is sold under different brand names like Clomid, Serophene, Fertomid, etc. This medicine comes under the class of non-steroidal medicine, which stimulates ovulatory functions. Clomid is taken by oral administration. It is known as the first line of treatment of infertility and gives an excellent quality of result.

Who can use Clomid (Clomiphene Citrate)?

Clomid can be used only in the patient of ovalutaory dysfunction with the following conditions:

  • Patient who are not pregnant.
  • Patient who has no ovarian cysts. Clomid (Clomiphene Citrate) is not indicated in a patient who is suffering from ovarian enlargement, except polycystic ovary syndrome.
  • Patients without unusual menstrual or vaginal bleeding.
  • Patients who has no liver disease.

What should one know before starting Clomid for pregnancy?

Before starting Clomid therapy, you must rule out the following important things:

  • Estrogen levels
  • Primary pituitary and ovarian failure
  • Endometrial carcinoma and Endometriosis
  • Uterine fibroids
  • Other factors of pregnancy 

Estrogen levels: The patients, who want to take this medicine, should have proper level of endogenous estrogen, because reduced amount of estrogen may not give you the favorable result.

Primary Pituitary and Ovarian Failure: Primary pituitary and ovarian failure, as it is a condition in which women's ovaries fail to produce eggs any more. Under such condition Clomiphene Citrate will not help in getting pregnant.

Endometriosis and Endometrial Carcinoma: Clomid is not a medicine to use in Endometriosis or endometrial carcinoma. In these conditions, the endometrial cells are found inside the uterus grows to the other parts of the body. So this medicine should be used before the endometrium biopsy.

Uterine fibroid: The medicine should be used with cautious in the patient with uterine fibroid since uterine fibroid has the tendency to grow fast.

Before starting Clomid therapy:

The patient under the treatment of Clomid should be well-observed with proper instructions. The physician will suggest the patient for Clomid therapy after evaluating and doing all the relevant diagnostic. The treatment plan should be well co-ordinate in advance. The physician will discuss all the possible pros and cons with the patient prior to the therapy. The ovulation occurs 5-10 days after the course of one cycle.

Before starting the therapy, your doctor will check your lower abdomen to evaluate any ovarian enlargement, like pituitary gonadotropin, polycystic ovary syndrome etc., to avoid any unwanted complication.

Dose of Clomid:

After the successful examination and diagnosis, your doctor will may advice a starting dose of one 50mg tablet, for 5days during your menstrual cycle. The doctor may advice for a higher dose of 100mg if, the patient does not respond for 50mg dose. The second therapy with increased dose should be started after 30 days of the first therapy.  It is not recommended to increase the dose or duration more than 5 days. 

What should you do if ovulation is not achieved? 

If ovulation is not achieved after the three complete cycles, further therapy of Clomid should be stopped according to the following evaluations:

  • If all the three ovulatory responses occur, but pregnancy is not achieved.
  • If menstruation is not occurred after the ovulartory response.

Long-term use for more than six cycles is not advised.