Dianette-Diane 35-Cyproterone Acetate 2mg + Ethinyl estradiol .035mg

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Dianette-Diane 35-Cyproterone Acetate 2mg + Ethinyl estradiol .035mg

Generic: Cyproterone Acetate 2mg + Ethinyl estradiol .035mg

Manufacturer: RSM/Dhadha

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Dianette Drugs

Dianette or Cyproterone is a synthetic medicine which comes under the class of steroidal anti-androgen, progestine and anti-gonadotropin. Antiandrogens are effective in blocking the action of hormone called testosterone. This results in reduced production of hormone testosterone in testicles. This is done by blocking the interactions of androgen with their respective receptors. It also suppresses the biosynthesis of androgen. This medication is used for the management of advanced prostate cancer. Discuss with your doctor before starting any dose of this medication. Always keep it in mind that this medication should not be given to anyone else to use who has the same symptoms, because it can be harmful to use this medication without consulting the physician.

The medicine works as a contraceptive by preventing the ripening and release of eggs from the ovaries, as well as increasing the thickness of the cervical mucus, which makes it more difficult for sperm to cross from the vagina into the womb. It also changes the lining of the womb so that it is less suitable for any fertilised eggs to successfully implant in.

How does dianette work?

Dianette or Cyproterone works by the following mechanisms:

  • It Blocks the receptors that interacts with the androgens. This makes the androgen become unable to effect on the skin and hair follicles. Thus it improves the acne and hirsutism.
  • Dianette or Cyproterone also reduces the synthesis of androgens by the ovaries. Thus, it reduces the circulating male hormones.
  • It acts as a contraceptive and prevents the ovaries to become mature and release the eggs from the ovaries.
  • It also thickens the cervical mucus that makes the sperm to cross the vagina into the womb.
  • It also alters the lining of the womb and makes it difficult for the fertilised eggs to implant in the womb.

What are the indications of Dianette?

Dianette or Cyproterone is indicated in the following conditions, such as:

  • In the patients of severe acne who don’t respond to oral antibiotics.
  • In the woman, who suffers from abnormal hair growth due to the increased production of male sex hormones.
  • This medicine can also be used as contraceptive for females, but you need to take doctor’s consultation before using it.

What are the contra-indications of Dianette?

This medication is contraindicated in the following conditions, like:

  • In the patient who is allergic to Cyproterone or any ingredient of this preparation.
  • If you are experiencing any serious liver disease.
  • In the person suffering from any renal disease.
  • In women, who is experiencing diseases like deep vein thrombosis, venous thromboembolism etc.
  • In females, who has diabetes, high blood pressure and other cardiovascular disorder.
  • In females, who has history of migraine.
  • If you are suffering from breast cancer or has history of breast cancer.
  • Women with a history of gallstone, jaundice, liver cancer etc.

Note: The above list is not complete. You should always talk to your doctor before using this medication for any purpose.

What are the possible side effects of this medication?

Each and every medicine has some side effects that occur in every individual in different way. Like other medication, this medication may also show some side effects. Some of the possible side effects are:

  • Nausea and vomiting
  • Migraine
  • Depression
  • Headache
  • Change in weight
  • Vaginal thrush
  • Skin infection
  • Breast tenderness
  • Water retention in the body
  • Loss of libido
  • Unusual menstrual bleeding
  • High blood pressure

This list of side effects is not complete. So if you catch any unusual symptoms while taking this drug, contact your physician immediately.

What are the drug interactions of Dianette?

To be in safer side, it is important to inform your health care provider or the pharmacy person if you are taking any other medications including any herbal products or other supplements. Because concomitant use of some drugs with this medication can causes serious complication for you. Some of the names of medications that can interact with Dianette are mentioned below:

  • Bosentan
  • Aprepitant
  • Carbamazepine
  • Cobicistat
  • Barbiturates
  • Modafinil
  • Oxcarbazepine
  • Phenytoin
  • Rifampicin
  • Ritonavir
  • Phenobarbital

What is dosage of Cyproterone or Dianette?

Each and every tablet of this drug contains the same dose. You can take one tablets daily for 21 days and then take a seven days off. After seven days, you should take the pack again after the seven days. Do not stop the medicine even if you are bleeding after seven days also.

In case of acne, you should take the medicines for three to four months to get the best result. 

What are the precautions of this medication?

You should take the following precautions while using this medication:

  • Do not take this medication if you are allergic to Cyproterone or any other ingredient of this this preparation.
  • Avoid this medication if you are suffering from hepatic and kidney disease.
  • You should not take this medication, if you have any history of breast cancer and migraine.
  • Dianette is contraindicated in the patients suffering from gallstone.
  • Cyproterone is prohibited in pregnancy and lactating women.
  • This medication is strictly not recommended in the patients of deep vein thrombosis or any other diseases related to blood vessels.

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