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Generic: Calcipotriene (kal-si-poe-TRY-een) Topical

Manufacturer: RSM/Dhadha

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Dovonex topical cream is used to treat Plaque psoriasis (psoriasis vulgaris) skin disease. It contains calcipotriol as active ingredient, which is a derivative of vitamin D. As the cream is applied on the affected area of skin it works by reducing the production of skin cells.

Psoriasis is the skin condition in which excessive skin cell production result in the scaling and thickening of the skin. Calcipotriol (the active content of this medication) affects the excessive skin cell synthesis and supports normal growth of the skin cells. All this result in flatten and clear the psoriasis plaques.

Continuous use of Dovonex helps to improve skin gradually. However, for seeing maximum improvement you have to wait up to 12 weeks of treatment.

What is Dovonex (calcipotriene)?

  • Dovonex (Calcipotriene) is a man made topical form of vitamin D, which plays a key role in the growth and development of skin cells.
  • Dovonex (Calcipotriene) topical is indicated as a treatment for plaque psoriasis (psoriasis with scaly patches).
  • This treatment may be used for other medical benefits as well other than those listed in this medication guide. 

What is the critical information that I should know before taking treatment with calcipotriene topical (Dovonex)?

  • Calcipotriene topical cream should be used only on the affected patches of the skin.
  • This cream must not be used on damaged, broken, sunburned or wounded skin.
  • Using harsh, or drying soaps during treatment may cause irritation on the skin so, avoid using this type of cleansers.
  • The maximum safe limit of this ointment is 100 grams in a week, do not use excess quantity. 

What are the points that I should include at the time of consultation about calcipotriene topical (Dovonex)?

  • The topical treatment of Calcipotriene comes in the FDA pregnancy category C. It may cause adverse effect on the health of an unborn baby; hence the treatment must be used after consulting a doctor if you are pregnant.
  • Calcipotriene topical cream may also pass into the breast milk and affect the health a new born. Consultation is required before starting this treatment if you are breast-feeding a baby.
  • Calcipotriene topical treatment should not be used on skin that is damaged, broken, sunburned or wounded skin as it could make your condition much worse.

What is the manner to use topical Dovonex?

  • Use Dovonex (calcipotriene) topical cream according to your prescription. In case of any confusion, contact your doctor or healthcare provider.
  • Wash hands before and after using this cream otherwise it can go into your eyes or nostrils and cause unwanted irritations.
  • Clean and dry the area of skin which has infection before applying Dovonex (calcipotriene) topical. Use the ointment only to the affected area.
  • Keep your eyes, mouth, face and open wounds safe from Dovonex. If medication gets in these areas mistakenly, rinse it off with water.
  • The treatment generally suggested to be used once or twice a day, as per your skin condition.
  • The calcipotriene topical should not be used more than recommended quantity and maximum quantity of use should not exceed the limit of 100 grams in a week.
  • To show the benefits, patients have to wait for at least 2 weeks of treatment. Continue treatment for the recommended duration without adjusting doses for getting full benefits.


How to store Dovonex cream?

  • Keep Dovonex cream (calcipotriene) topical at room temperature away from moisture and heat.
  • This cream should not be refrigerated.


What may happen if someone has missed a regular dose of Dovonex?

In case of missed dose, nothing to worry just apply dose as soon as you remember. In case it is almost time for next dose, then you can skip the missed dose and tag along to your next schedule.


What may happen if I overdose with Dovonex? 

In case of overdose, contact emergency healthcare provider. In such condition, patient may get symptoms of overdose such as weakness, fatigue, drowsiness, dizziness, headache, skin irritation, nausea, vomiting, and high levels of calcium in the blood.


What are possible interactions of topical Dovonex?

During treatment, avoid using harsh, abrasive, or irritating cleansers on the affected area of the skin. Other than this, do not use cosmetics and perfumes on the affected area. Using other topical treatment may also cause problem, hence ask your doctor before using two or more topical treatments on the affected area concomitantly. 

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