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Darvocet is a medicine of pain reliever with a combination of propoxyphene and acetaminophen. Together, these drugs work better in the treatment of the pain. Pain is not a disease, but a symbol that gives the indications that something in the body is not perfect. You can buy this drug from our site www.buymeds247online.com at a very affordable price.

Product description of Darvocet-

Darvocet falls under the category of the drugs called narcotic pain relievers. Propoxyphene is a drug of weak narcotic pain relieving category. It gets bind to the opiate receptors in the brain and blocks the passage of pain transmission. Acetaminophen is analgesic category drugs that also reduce fever and potentiate the effect of propoxyphene. Acetaminophen blocks the production of the prostaglandin in the CNS and also acts peripherally to inhibit the impulse of the pain.

Uses of Darvocet-

Darvocet is indicated for treating mild to moderate pain, also in the management of the post-operative pain during dental care.

Dosage of Darvocet-

Darvocet is intended to administer orally with water. The dose of the drug depends on the severity of the pain and patient response.

  • Darvocet-N 100: recommended dose is one tablet every 4 hours as required for pain. The dose of Darvocet –N 100 should not increase more than 6 tablets in a day.
  • Darvocet-N 50: recommended dose is two tablets every 4 hours as required for pain. The dose of Darvocet-N 50 should not increase more than 12 tablets per day.

Do not exceed the daily maximum dose of the drug.

Side-effects of Darvocet-

Less serious side effects are headache, dry mouth, itching, may lead to constipation and signs of some allergic reactions are pimples, difficulty in breathing, swelling of face, tongue, lips or throat.

Some severe signs that can be seen are pain chest, nausea, confusion, dilemma, seizure, loss of appetite, dark urine, may lead to jaundice, drowsiness, blurring of the vision, unusual behavior, etc.

Storage condition of the Darvocet-

Store the drug at room temperature 15-30 0C. Protect the drug from moisture and heat. Keep the medicine away from the reach of children and pets.

Interactions of Darvocet-

As Darvocet is a combination of both propoxyphene and acetaminophen so interactions can be caused by both the drugs.

  1. Interaction with propoxyphene:
  • Propoxyphene shows interactions with CYP3A4 inhibitors like ritonavir, ketoconazole, diltiazem, verapamil, grape fruit juice, erythromycin, etc.
  • Warfarin can also interact to cause the bleeding
  • CNS depressants (diazepam, alprazolam, Phenobarbital, pentobarbital), alcohol or anesthetics (ketamine, thiopental, desflurane)
  • Agonist/antagonist opioid analgesics- pentazocaine, buprenorphine
  • Monoamine oxidase inhibitors- selegiline, isocarboxazid, phenelzine.
  1. Interaction with acetaminophen:
  • Alcohol, oral contraceptives, lamotrigine, probenecid. Zidovudine,
  • Beta blockers- propranolol, toprol, nadolol.
  • Anticholinergic- ipratropium, tiotropium.
  • Loop diuretics- torsemide, furosemide and bumetanide.

Contraindication of Darvocet-

  • In nursing mother as it passes in milk during lactation.
  • During pregnancy.
  • If hypersensitive to propoxyphene and acetaminophen.  

Warning and Precautions-

Some precautions that should be followed while taking Darvocet-

  • Warning for those who are easily prone to addiction.
  • Should be used with caution who is taking any tranquilizers.
  • Avoid drinking grape fruit juice and eating grape fruit along with medication of Darvocet.
  • Avoid alcohol while using Darvocet. Also avoid the work that requires the alertness.
  • Take the recommended dose otherwise it may cause drug dependence at higher doses or if used for a long time.
  • Darvocet is used with caution in patient who is suffering from renal impairment and hepatic problems.

Missed dose of Darvocet-

If you are on regular dosing of Darvocet then do not miss any dose. If you missed it take the drug as soon as you remembered. Omit it if it is the time for next scheduled dose.

Overdose of Darvocet-

Follow the dose as recommended to you. In case of overdose visit the nearest clinic or consult your doctor. Symptoms that can be seen while Darvocet overdosing are extreme sleepiness, nausea, vomiting, weak pulse, uneven heart rate, fainting, sweaty and sticky skin, convulsions or seizures can be felt.

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