ED Trial Mix Sample Pack

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ED Trial Mix Sample Pack

Generic: Sildenafil, Tadalafil, Vardenafil

Manufacturer: RSM/Dhadha

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ED Trial Mix Pack contains combination of medicine that are very effective in the treatment of various sexual problem of male. It is used to treat erectile dysfunction in man. This pack consists of medicine namely, Sildenafil, Tadalafil and Vardenafil. All these medicine belong to the group of drug known as phosphodiesterase type 5 inhibitors.

These medicines do not provide protection against sexually transmitted disease such as syphilis, HIV, hepatitis B, gonorrhoea, etc.

Tadalafil is also available in other brand that is useful in the treatment of high blood pressure in the lungs, a condition commonly known as pulmonary arterial hypertension.

The patient should not share this medicine with any other person else it might lead to serious side effects to them. 

The medicines in ED Trial Mix Pack contains three medicines namely, Tadalafil, Sildenafil, Vardenafil. These medicines are used to treat impotence, erectile dysfunction (inability to maintain or attain penile erection). In addition to this, the medicines are also used to treat Benign Prostatic Hyperplasia (BPH). All medicines in ED Trial Mix Pack belong to the group of medicine known as phosphodiesterase type 5 inhibitors.

These medicines should be stored at a temperature that varies from 15-30 degree centigrade. It should be protected from light, heat and moisture. The patient should always keep the medicine at such a place where child and pet should not reach. The user should properly check for the expiry date of the medicines before taking it. 

 Mechanism of action: 

These medicines are responsible for making the muscles smooth so that the blood stream present in the penis get enhanced and arouses erection.

In combination with sexual stimulation, the medicine in the ED trial pack helps the blood to flow into the penis so that it can achieve and maintain erection. This filling occurs due to blood vessels that bring blood to the penis, increase in size and deliver more blood to the penis. Simultaneously, the blood vessels takes blood away from the penis, decreases in size and remove less blood from penis.

Sexual stimulation also leads to the production and release of nitric oxide in the penis. This nitric oxide helps the enzyme guanylate cyclase to produce cyclic guanosine monophosphate.  Cyclic guanosine monophosphate is mainly responsible for increasing and reducing the size of blood vessels that carries blood to and from the penis respectively and, thus causing erection. When cyclic guanosine monophosphate is degraded by other enzyme, phosphodiesterase-5, the blood vessel return to their normal size, blood leaves the penis and the erection ends. The medicine Tadalafil prevents the phosphodiesterase-5 from destroying from destroying cyclic guanosine monophosphate it remains for long time. Longer stay of cGMP leads to more prolonged engorgement of penis with blood.



The medicines in the ED trial mix pack is known to treat erectile dysfunction in case of men. 

Side effects: 

Some of the common side effects exhibited by the patient after using medicines in the ED trial sample pack are:

  • Allergic reaction such as rash, itching, swelling in face, throat, tongue, etc.
  • Decreased vision
  • Non-arteritic anterior optic neuropathy (NAION)
  • Heart problem
  • Headache
  • Facial flushing
  • Stomach upset
  • Nausea
  • Chest pain
  • Heart attack
  • Palpitation
  • Increase heart rate
  • Stroke
  • Prolonged erection
  • Muscle pain
  • Nasal stiffness 

Drug Interactions: 

Some of the drug that might interfere with the medicines in the ED trial sample pack are: 

  • Clarithromycin
  • Erythromycin
  • Telithromycin
  • Bosentan
  • Telaprevir
  • Atazavir
  • Delavirdine
  • Saquinavir
  • Carbamazepine
  • Imatinib
  • Nefazodone
  • St. John’s wort  
  • Itraconazole
  • Ketoconazole
  • Boceprevir
  • Fosphenytoin
  • Primidone
  • Isoniazid
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Posaconazole
  • Voriconazole
  • Amlodipine
  • Nicardipine
  • Quinidine
  • Nevirapine
  • Ritonavir
  • Oxcarbazepine
  • Phenobarbital
  • Phenytoin
  • Efavirenz
  • Fosamprenavir
  • Indinavir
  • Nelfinavir



The recommended dose for Tadalafil and Sildenafil initially should be 10 mg per day to be taken before physical intercourse. Based on the tolerance   power, requirement of the body and effectiveness, the dose can further be increased to 20 mg or decreased to 5 mg.

The patient should this medicine once in a day, with or without food. This medicine should be taken at least half an hour prior to physical intercourse. 

Missed dose: 

In case of missed dose, the patient should consult to the doctor. 


If overdose is suspected, the patient should consult to their medical advisor else it might lead to serious health problem. 


  • Before taking these medicines, the patient should tell to the doctor if they are allergic to it or have any other allergy.
  • The various inactive ingredients present in the medicines might also be responsible for causing allergic reaction in some of the users. Care should be taken for this.
  • The patient, if taking any medicine that contains nitrate in it, should tell to the doctor before the treatment with this medicine as it lead to sudden decrease in the blood pressure.
  • If the patient had suffered from retinitis pigmentosa that is an inherited condition of eye or Peyronie’s disease, then they should tell to the doctor prior using these medicines.
  • The drug results in the dizziness in patient and therefore, the work that requires clear vision or alertness should be avoided by the patient.
  • Alcohol and alcoholic beverages should be limited while using these drugs.
  • To reduce the dizziness and light-headedness, the patient should get up slowly if they are rising from sitting or lying position. 

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