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Generic: Desvenlafaxine

Manufacturer: RSM/Dhadha

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Desvenlafaxine is a useful medicine that is used for the treatment of depression.
  • What is Pristiq?

Desvenlafaxine succinate is the generic name of Pristiq. It is classified in category of Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) medication. Pristiq is an antidepressant medicine that is widely used for managing major depressive disorder. Desvenlafaxine influence the chemicals present in the brain that may be cause behind depression. Pristiq is prescribed to balance the Serotonin and Noradrenaline chemicals that work as communicators between certain nerves in the brain to work helps to restore feeling of wellness.

  • What are the medical benefits of Pristiq as an anti depressant medication?

Pristiq is indicated to treat and prevent the relapse of depression. Patient should use this drug under medical supervision as misuse can lead to unwanted adverse effects. Medication can be used for other purposes as well that are not included here.

  • What is the general dosing schedule of this treatment as an anti depressant?

Normally, Pristiq (desvenlafaxine) is prescribed with 50 mg dose to be taken as a single dose daily. Patient can take this drug with or without meal. Though, higher dosages may also be prescribed according to the need of patient, but the possibilities of getting side effects is more with higher dosages.

  • Are there any precautions that one should know for reducing risks and completing safe treatment with Pristiq?

In following medical condition, your treatment with Pristiq can get affected and may outcome as unsafe and meaningful:

  • Existing or history of seizures or convulsions
  • bipolar disorder
  • Blood pressure problems
  • Eye problem like Glaucoma
  • Already on any blood thinning medication
  • Increased cholesterol level
  • Disease related to kidneys or liver
  • Heart disease
  • Imbalance of sodium levels in blood
  • Pregnant or breast feeding a baby as it belongs to Category C drug according to FDA
  • Allergies to any drug especially with any contents of Pristiq.


  • Are there any possibilities that the treatment with Pristiq may interact with any other drugs if used concomitantly?
  • Monoamine oxidase inhibitors (MAOIs) such as phenelzine (Nardil), isocarboxazid (Marplan), and others,
  • Other antidepressants,
  • Migraine medications,
  • Pain relievers such as tramadol (Ultram),
  • Antibiotic medicines like linezolid (Zyvox),
  • Ketoconazole (Nizoral),
  • ibuprofen (Advil, Motrin),
  • warfarin (Coumadin) and
  • Aspirin

Above is not the only drugs that can affect your medication of Pristiq, some other drugs may also influence the working of this medication. To cut down the possibilities of adverse effects of drug interaction, inform your doctor about all your medicinal products currently in use. Also, consult your doctor if you start or drop any treatment during taking Pristiq.

  • What may be the possible side effects of this treatment?

Side Effects that are frequently reported by patients include:

  • Headache,
  • Nausea,
  • Diarrhea,
  • Increased sweating and dry mouth,
  • Feeling nervous, sleepy or having trouble sleeping (insomnia).

Rare Side Effects that are not common but are of serious nature:

  • Increased heart rate,
  • Low blood pressure,
  • Increased salivation,
  • Irregular menstrual cycle,
  • Frequent urination,
  • Unreasonable bleeding,
  • Low sodium level in body which may cause headache, tiredness, and problem in concentrating.

If you observe any other abnormal symptom that has started after initiating treatment with this medication, talk to your doctor.

  • What is the Generic name of Pristiq and its pharmacological class?

Generic name: Desvenlafaxine

Pharmacological or Medication class: Antidepressant of Serotonin-norepinephrine reuptake inhibitor (SNRI) class

  • How much time do Pristiq take to show its healing effect?

Normally, the disorders associated with sleep, appetite or energy is likely to get better within the initial 1-2 week treatment. The basic signs of improvement in these physical symptoms symbolizes you’re your medication is working. Serious symptoms associated with depressed mood and coldness to activities in surrounding might require up to 6 to 8 weeks to fully get better.

  • Does Pristiq come with special caution to pregnancy?

Female patients should be careful in choosing any medication if they are planning to conceive or pregnant. Inform your doctor preceding treatment for these conditions. Caution is advised to breastfeeding mothers as well because desvenlafaxine can pass into breast milk.



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