Sildenafil Citrate 100 MG

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Sildenafil Citrate 100 MG

Generic: Sildenafil Citrate 100mg


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Sildenafil is an important medicine that belongs to the class of drug known as phosphodiesterase-5 inhibitor. Along with sexual stimulation, it increases the blood flow into the penis at the time of physical intercourse. This is beneficial in achieving and maintaining erection.

Sildenafil is used for treating sexual functional problem such as impotence or erectile dysfunction in case of male. The whole process is carried out with the help of enzyme phosphodiesterase type 5 in the body.

Furthermore, Sildenafil citrate is also used to treat high blood pressure in the lungs a condition that is known as pulmonary arterial hypertension. 

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Sildenafil citrate is very powerful and effective medicine that is used to treat erectile dysfunction in male. In addition, this medicine is also used to treat pulmonary arerial hypertension (PAH).  It is available in the market under the brand name of Viagra, Revatio, etc.

Initially, this medicine was developed and marketed by a United States based pharmaceutical company, Pfizer.

It does not provide any protection against sexually transmitted disease such as HIV, syphilis, gonorrhoea, etc. Therefore proper precaution should be taken by the patient.

Sildenafil citrate should be stored at room temperature that varies from 15-30 degree centigrade. It should be protected from light, heat and moisture. This medicine should be kept at such a place where pet and child should not reach. 

 Mechanism of action: 

Sildenafil citrate works by inhibiting the enzyme, (cGMP) cyclic guanosine monophosphate-specific phosphodiesterase type 5 (PDE5). This enzyme degrades cGMP that regulates blood flow in the penis. Nitric oxide is released in the presence of sexual stimulation. This nitric oxide reacts inside penis and form an enzyme cyclic guanosine monophosphate (cGMP), cGMP is known to loose and relax the arterial wall of the penis and thus, erection is created. Once the artery of the penis is loosened, it becomes easily engorged with blood. Once, the arteries are swollen, an erection is created.

Another enzyme called phosphodiesterase-5 is also present in the penis that helps in achieving better and long lasting erection. This phosphodiesterase enzyme is known to degrade and reduce cyclic guanosine monophosphate within penis. This degradation is essential; else there will be constant erection.



Sildenafil citrate is used to treat impotence or erectile dysfunction in case of male.


Side effects: 

Some of the side effects that the patient might get after the intake of Sildenafil citrate 100 mg are: 

  • Dizziness
  • Light-headedness
  • Heartburn
  • Flushing
  • Problem in sleeping
  • Edema
  • Increased sensitivity to light
  • Blurred vision
  • Difficulty in differentiating between blue and green colour
  • Nausea
  • Faintness
  • Pain in chest
  • Ringing in the ears 


Drug Interactions: 

Some drugs might interfere with Sildenafil citrate are: 

  • Doxazosin
  • Isosorbide
  • Nitroglycerin
  • Nitroprusside
  • Itraconazole
  • Ketoconazole
  • Cimetidine
  • Ritonavir
  • Saquinavir
  • Delavirdine
  • Erythromycin
  • Dihyrocodeine
  • Trlithromycin
  • Bosentan
  • Rifampin
  • Rifabutin
  • Prazosin
  • Terazosin
  • Amyl nitrite
  • Carbamazepine
  • Phenobarbital
  • Phenytoin
  • St. John’s wort



The medicine should be taken orally only when needed. The patient should take the tablet of Sildenafil citrate at least half an hour prior physical intercourse. This medicine should be taken only once in a day. While taking the medicine, fatty or high-fat meal else the drug will take more time to show its effect. The recommended dose for Sildenafil citrate is 50 mg only when needed. Based on the effectiveness and tolerance capacity for the drug and requirement of the body, the dose can be increases to 100 mg or decreased to 25 mg.



If overdose is suspected, the patient should consult to the doctor as soon as possible.



  • Before taking this medicine, the patient should tell to the doctor in case they are allergic to this medicine.
  • If the patient is taking any prescribed, non-prescribed or herbal product then they should inform their health care provider.
  • The user of Sildenafil citrate is having allergy with any food items, preservative, dyes or any other medicine or the inactive ingredients present in the tablet, then they should tell to the doctor before taking the medicine.
  • If the patient is having deformed penis such as cavernosal fibrosis, Peyronie’s disease, blood cell problem such as leukemia, myeloma, sickle cell anaemia or any other problem that can increase the risk of prolonged erection then they should tell to the doctor.
  • Those patients suffering from heart problem and taking Sildenafil citrate are at great risk of developing heart related side effects such as heart attack, stroke, pain in chest, neck or jaw, numbness, headache, nausea, stomach pain, etc. If they are experiencing such problem after taking the medicine then they should consult to the doctor.
  • If the patient is having any medical history of prolonged or painful erection, macular degeneration, eye problem, retinitis pigmentosa, optic neuropathy, drastic vision loss, hearing problem such as decreased hearing, ringing in ear, etc.
  • Consult with your doctor if you are experiencing any liver, lung or kidney problem, hypertension, ulcer, blood vessel problem, heart attack, stroke, tachycardia.