Viagra | Sildenafil Citrate

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Viagra | Sildenafil Citrate

Generic: Viagra

Manufacturer: RSM/Dhadha

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$0.60

Generic Viagra is the most widely prescribed drug to manage the erectile dysfunction in male. The active ingredient of this medication is sildenafil citrate. This medicament influences and increases the natural process of erection by dilating the blood vessels of the penis and relaxes smooth muscles of the penis. When the dilated arteries are filled with blood, the corpus cavernosa get engorged in the penis and thus the penis becomes erect. It is a prescribed medicine. The medicine can be taken with food or without food. The patient should take this medicine at least 20 minutes before physical intercourse. 

Additional Information

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Side Effects No
precaution No
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Generic Viagra is used to treat the male sexual problem such as impotence or erectile dysfunction. This medicine does not provide protection against sexually transmitted disease such as HIV, hepatitis B, gonorrhoea, syphilis, etc. 

Sildenafil also inhibit the enzyme phosphodiesterase-5 that destroy cGMP and allow cGMP to accumulate and persist for long time. Longer persistence of cGMP results in prolonged engorgement of the penis.

In addition, Sildenafil is also known to reduce pressure in the pulmonary artery. This medicine is used for treating high blood pressure in lungs, a condition known as pulmonary arterial hypertension.

Generic Viagra contains sildenafil citrate as active ingredient that is chemically designated as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate. This appears as white to off-white coloured crystalline powder that has a molecular weight of 666.7. the film-coated, blue coloured tablet of generic Viagra is round-diamond in shape. It also contain various inactive ingredients such as microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, lactose, triacetin, and FD & C Blue #2 aluminium lake.       

 Mechanism of action: 

This medicine works by blocking the enzyme phosphodiesterase in the body. In combination with sexual stimulation, sildenafil functions by helping the blood flow into the penis to achieve and maintain erection

Penile erection is caused by the engorgement of the penis with blood. This occurs with the help of blood vessels that delivers blood to the penis and increase the supply of blood. This blood vessel carries away blood from the penis and decreases the removal of blood. In general, because of sexual stimulation, nitric oxide is produced and released in the penis. This nitric oxide is responsible for activating the enzyme, guanylate cyclase that produces cyclic guanosine monophosphate (cGMP). cGMP is mainly responsible for erection by affecting the amount of blood that the blood vessels delivers and remove from the penis.

 

Indication: 

This medicine is used to treat erectile dysfunction in male. It is also used in the treatment of pulmonary arterial hypertension.

 

Side effects: 

Some of the common side effects experienced by the patients after taking generic Viagra are:

  • Warmth or redness of face, neck or chest
  • Headache
  • Stomach upset
  • Diarrhoea
  • Allergic reactions
  • Prolonged erection
  • Vision change
  • Sudden loss of vision
  • Ringing in the ear
  • Swelling in ankle/feet
  • Shortness of breathing
  • Light-headedness
  • Fast/irregular heartbeat
  • Cheat pain

 

 

Drug Interactions: 

Some of the drugs that might interact with generic Viagra are: 

  • Imatinib
  • Cimetidine
  • Bosentan
  • Nefazodone
  • St.John’s wort
  • Clarithromycin
  • Erythromycin
  • Telithromycin
  • Fluconazole
  • Itraconazole
  • Ketoconazole
  • Posaconazole
  • Voriconazole
  • Amlodipine
  • Amiodarone
  • Nicardipine
  • Quinidine
  • Telaprevir,
  • Boceprevir
  • Efavirenz
  • Fosamprenavir
  • Isoniazid
  • Rifabutin
  • Rifampin
  • Carbamazepine
  • Phenobarbital

 

Dosage:

Initially, the patient is given 50 mg generic Viagra or Sildenafil citrate at least one hour prior physical intercourse. Based on the effectiveness and tolerance capacity of the drug by the body, the dose can be increased to 100 mg or can be decreased to 5mg. The patient should take this medicine once in a day.

 

Missed dose: 

In case the patient misses the dose, they should contact to the doctor as soon as possible to avoid any unwanted response.

 

Overdose: 

If the patient takes excess medicine, then they should consult to the doctor. Overdose of the medicine might lead to serious side effects to the patient.

 

 Precautions: 

  • Prior taking generic Viagra, the patient should tell to the doctor if they are allergic to this medicine or have any other allergy. Sometimes, the inactive ingredients might also lead to allergic reaction in some of the users.
  • In case the patient is taking any nitrate medicine, then they should not take generic Viagra. Some of the nitrates containing medicines are Nitroglycerin, Isosorbide dinitrate, Isosorbide mononitrate, amyl nitrate, etc. Taking these medicines might result in lowering of blood pressure.
  • The patient should tell to the doctor if they are suffering from heart disease, coronary artery disease or have a recent heart attack in the past 6 month, stroke or congestive heart failure.
  • If the patient has any bleeding disorder, haemophilia, stomach ulcer, retinitis pigmentosa, physical deformity of penis such as Peyronie’s disease, then they should tell to the doctor before taking this medicine.
  • The patient, if taking any prescription, non-prescription or drugs or herbal products, then they should tell to the doctor.
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